Growth Factor in Cultured Fibroblasts Cyclin D1 Messenger RNA Is Inducible by Platelet-derived
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چکیده
In fibroblasts in culture, the levels of cyclin Dl niRN \ are growth regulated. In mouse and in human fibroblasts, both serum and plateletderived growth factor increase cyclin Dl mRNA levels with similar kinetics of induction. Insulin-like growth factor 1 by itself does not induce cyclin Dl expression, and an antisense oligodeoxynucleotide to the insulin-like growth factor 1 receptor RNA does not affect the growth-regulated levels of cyclin Dl mRNA.
منابع مشابه
Cyclin Dl Messenger RNA Is Inducible by Platelet-derived Growth Factor in Cultured Fibroblasts1
In fibroblasts in culture, the levels of cyclin Dl niRN \ are growth regulated. In mouse and in human fibroblasts, both serum and plateletderived growth factor increase cyclin Dl mRNA levels with similar kinetics of induction. Insulin-like growth factor 1 by itself does not induce cyclin Dl expression, and an antisense oligodeoxynucleotide to the insulin-like growth factor 1 receptor RNA does n...
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